THE EFFECT OF ANTI HYPERTENSIVE DRUGS ON TEAR SECRETION AND STABILITY

Hypertension is a chronic medical condition in which blood pressure the arteries elevated. This research work studied effect of antihypertensive drugs specifically beta adrenergic blockers (atenolol) and angiotensin converting enzymes (lisinopril) on tears secretion stability adults. A total 75 people (35 65years) male female participated completed study with mean age 52.8±1.83years. These subjects were divided into group (control) comprised 25 normotensive subjects; B (experimental) hypertensive atenolol alone (beta blocker) C lisinopril (angiotensin ) .Tear volume was determined using schirmer strips tear fluroscein strip. patients examined for all tests at first week (baseline) repetition one later after oral drug administration (Group B) or C). When break up time baseline follow measurement compared, it observed that there statistically significant decrease (P<0.05). breakup measurements Group decreased.(P<0.05) The use has an time. Also enzyme inhibitor)